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Cheptea C. Optimized synthesis and spectral characterization of some hydrazones based on 5-nitroindazole with pharmacological potential [Електронний ресурс] / C. Cheptea, L. M. Ivan, D. O. Dorohoi, V. Sunel, I. Hurjui, C. I. Saveanu, A. I. Galaction // Ukrainian journal of physics. - 2014. - Vol. 59, № 3. - С. 313-318. - Режим доступу: http://nbuv.gov.ua/UJRN/Ukjourph_2014_59_3_20 A number of new hydrazones with biological activity are synthesized on the basis of 5-nitroindazole. The most efficient conditions of their synthesis with maximum reaction yield are established. The chemical structure of new compounds is found by the elemental analysis, FTIR spectroscopy, and <^>1H-NMR method. The data of spectral analysis were verified by calculations with the HyperChem software. Toxicological tests indicate that the synthesized hydrazones have the antitumor effect.
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Cheptea C. Optimized synthesis and spectral characterization of some hydrazones based on 5-nitroindazole with pharmacological potential [Електронний ресурс] / C. Cheptea, L. M. Ivan, D. O. Dorohoi, V. Sunel, I. Hurjui, C. I. Saveanu, A. I. Galaction // Український фізичний журнал. - 2014. - Т. 59, № 3. - С. 315-321. - Режим доступу: http://nbuv.gov.ua/UJRN/UPhJ_2014_59_3_20 A number of new hydrazones with biological activity are synthesized on the basis of 5-nitroindazole. The most efficient conditions of their synthesis with maximum reaction yield are established. The chemical structure of new compounds is found by the elemental analysis, FTIR spectroscopy, and <^>1H-NMR method. The data of spectral analysis were verified by calculations with the HyperChem software. Toxicological tests indicate that the synthesized hydrazones have the antitumor effect.
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